Searchable abstracts of presentations at key conferences in endocrinology

ea0029p310 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Alterations of protein expression profiles in 3T3-L1 adipocytes by interleukin 4

Chang Y. , Chen S. , Chiu Y. , Tsao C. , Shiau M.

Obesity, characterized by excess intra-abdominal adipose tissue, is closely associated with a cluster of metabolic disorders such as type 2 diabetes mellitus (T2DM). Our previous study revealed significant associations between interleukin 4 (IL4) genotypes and T2DM, as well as IL4 genotypes and high density lipoprotein-cholesterol levels. Our most recent study results reveal that IL4 has anti-hyperglycemic function by improving insulin sensitivity and glucose tolerance. In add...